Guifang Han, Qiang Wang, Yu‐Xin Liu
Nov 4, 2014
Citations
0
Influential Citations
48
Citations
Journal
Organic letters
Abstract
Copper-mediated intramolecular trifluoromethylation of N-phenylcinnamamides coupled with cyclization and dearomatization was used to construct various trifluoromethylated 1-azaspiro[4.5]decanes in moderate to high yields and with excellent regioselectivity and diastereoselectivity.