L. N. Chavan, Krishna Kumar Gollapelli, Rambabu Chegondi
Apr 13, 2017
Citations
0
Influential Citations
49
Citations
Journal
Organic letters
Abstract
Cp*Co(III)-catalyzed C-H functionalization cascade of N-methoxyamides with alkynedione has been reported for the synthesis of indolizidine scaffolds under redox-neutral conditions. The reaction displays broad functional group tolerance along with excellent yield. The reaction proceeds with kinetically relevant C-H bond activation through carboxylate assistance with excellent diastereoselectivity and complete opposite selectivity with respect to alkyne insertion.