M. Barlattani, G. Guglielmi, A. Mammarella
1979
Citations
0
Influential Citations
1
Citations
Quality indicators
Journal
Arzneimittel-Forschung
Abstract
N-Methyl-N-(beta-hydroxyethyl) guanidine O-phosphate (creatinol O-phosphate, COP) was checked on patients suffering from inadequate coronary circulation (12 patients had a recent myocardial infarction and 13 were suffering from angina pectoris) versus a reference substance (solvent of COP) in a double blind study. COP improved rhythm disturbances, chest pains and symptoms of contractility failure to a statistically significant degree.