A. M. Shestopalov, Yuliya M. Emeliyanova, A. A. Shestopalov
Sep 15, 2003
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Influential Citations
65
Citations
Journal
Tetrahedron
Abstract
Abstract To develop a method of synthesis of the potentially physiologically active compounds, 1′-substituted 6-amino-spiro-4-(piperidine-4′)-2 H ,4 H -pyrano[2,3- c ]pyrazoles, we studied the three-component condensation of substituted piperidin-4-ones, malononitrile and pyrazolin-5-ones. It was found that the electrochemical method of synthesis is more regioselective, the products of the reaction are analytically pure and do not require further recrystallization.