Carson W. Wiethan, Christopher M. Lavoie, A. Borzenko
Jun 14, 2017
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0
Influential Citations
10
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Journal
Organic & biomolecular chemistry
Abstract
The nickel-catalyzed cyclization of in situ generated ortho-chlorobenzophenone hydrazone derivatives, to afford 3-(hetero)aryl-1H-indazoles, is documented for the first time. The product 1H-indazoles can be transformed subsequently in a one-pot procedure into 1,3-di(hetero)aryl-1H-indazoles via copper-catalyzed N-arylation with (hetero)aryl bromides.