T. Akiyama, K. Daidouji, K. Fuchibe
Sep 6, 2003
Citations
0
Influential Citations
40
Citations
Journal
Organic Letters
Abstract
The catalytic, enantioselective [2 + 2] cycloaddition reaction of 1-methoxyallenylsilanes with α-imino ester has been achieved by means of the [Cu(MeCN)4]BF4/(R)-Tol-BINAP catalyst to afford 3-methylene-azetidine 2-carboxylates in good yields and with excellent enantiomeric excesses. The acid-catalyzed ring opening of the azetidines afforded chiral acylsilanes quantitatively.