N. Rostovskii, P. Sakharov, M. Novikov
Aug 14, 2015
Citations
0
Influential Citations
34
Citations
Journal
Organic letters
Abstract
A stereoselective and high-yield synthesis of hexahydropyrrolo[3,4-b]pyrroles from tetramic acids and 2H-azirines under Cu(I)-NHC catalysis is developed. An unusual N-C2 azirine bond cleavage, initiated by a copper enolate, was rationalized in terms of a free radical reaction mechanism.