Xianhua Pan, Q. Cai, D. Ma
Apr 27, 2004
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Influential Citations
156
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Quality indicators
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Organic letters
Abstract
The CuI-catalyzed coupling reaction of vinyl halides with amides or carbamates proceeds well at room temperature to 80 degrees C in dioxane to give enamides using N,N-dimethylglycine as the promoter and Cs(2)CO(3) as the base. The geometry of the C-C double bond is retained during the reaction course. [reaction: see text]