Y. Sakakibara, Y. Ido, K. Sasaki
Sep 1, 1993
Citations
0
Influential Citations
44
Citations
Journal
Bulletin of the Chemical Society of Japan
Abstract
The cyanation of 3-bromopyridine catalyzed by in situ generated Ni(PPh3)n was examined with various MCN (M = K, Na)-dipolar aprotic solvent systems by four procedures. Under certain reaction conditions, 3-bromopyridine and several heteroaromatic halides were cyanated to give the corresponding nitriles in fair to good yields. Noticeable differences in reactivity among 3-bromopyridine, 3-bromofuran, 3-bromothiophene, and bromobenzene were observed.