Zhengwang Chen, Peiwen Liang, Jing Zheng
Oct 3, 2018
Citations
1
Influential Citations
4
Citations
Journal
ACS Omega
Abstract
A direct and rapid method for the synthesis of α-iminonitriles achieved good to excellent yields. A novel intermolecular dehydration reaction between 2-aminopyridines and nitroalkenes is reported via a rare-earth-metal catalyst. The merits of this transformation include cyanide-free protocol, short reaction time, simple operation, water as the only byproduct, commercially available reagents, good functional group tolerance, etc. Moreover, nitroalkenes are demonstrated as a new “CN” source in this transformation.