H. Asahara, Kyo Muto, N. Nishiwaki
Sep 16, 2014
Citations
0
Influential Citations
11
Citations
Journal
Tetrahedron
Abstract
Abstract A practical, convenient, and safe cyano(nitro)methylation method was developed, in which cyano-aci-nitroacetate served as a synthetic equivalent of anionic nitroacetonitrile. A control of the single/double Michael additions was achieved, which enabled the synthesis of unsymmetrical double Michael adducts. Moreover, the Michael adducts can be used as precursors of pyridine and naphthyridine frameworks.