BY J. F. KuO, P. Greengard
Dec 1, 1969
Citations
2
Influential Citations
603
Citations
Quality indicators
Journal
Proceedings of the National Academy of Sciences of the United States of America
Abstract
Adenosine 3',5'-monophosphate-dependent protein kinase activity was found in about thirty sources including many mammalian tissues as well as species representative of eight different invertebrate phyla. The data support a unifying theory for the mechanism of action of adenosine 3',5'-monophosphate, namely that its many and diverse effects are mediated through activation of tissue-specific protein kinases.