J. Hanusek, Pavel Drabina, M. Sedlák
Sep 1, 2006
Citations
0
Influential Citations
11
Citations
Journal
Journal of Heterocyclic Chemistry
Abstract
Acylation of 2-amino-N-methyl-thiobenzamide with substituted benzoyl chlorides has been used to synthesize the corresponding 2-benzoylamino-N-methylthiobenzamides. Subsequent sodium methoxide-catalyzed ring closure gives the corresponding 3-methyl-2-phenylquinazoline-4-thiones. These compounds were characterized by means of their 1H- and 12C-NMR spectra. The kinetics of the cyclization reaction has been followed with UV-VIS spectroscopy at 100 °C in methanolic solutions of sodium methoxide.