J. H. Babler, William Bauta
Feb 5, 1985
Citations
0
Influential Citations
14
Citations
Journal
Tetrahedron Letters
Abstract
Abstract Treatment of 6-bromo-1,2-epoxyhexane (1) with one quivalent of sec -butyllithium afforded a 95:5 mixture of cyclopentylmethanol (4): cyclohexanol in approximately 40% yield. An analogous tandem metal-halogen exchange/cycloalkylation process using the oxirane derivative (2) of 6-iodo-1-hexene gave virtually the same mixture of alcohols in >60% yield.