T. B. Patrick, Mehrdad Shadmehr, Akbar H. Khan
Feb 19, 2013
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Journal
ChemInform
Abstract
Diethyl (E)-2-fluoromaleate (II), easily accessible via a Horner—Wadsworth—Emmons Wittig procedure, undergoes [3 + 2] cycloadditions with aromatic α-iminoesters (I) and aromatic nitrones (IV) to furnish polysubstituted pyrrole (III) or isoxazole derivatives (V), resp., in excellent regio- as well as stereoselectivity.