A. V. Vypolzov, D. Dar'in, S. Ryazanov
Apr 14, 2011
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Influential Citations
12
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Journal
Chemistry of Heterocyclic Compounds
Abstract
The reaction of benzamidines with 2-bromo- and 2-iodobenzaldehydes catalyzed by the CuI/L-proline system has been studied. Reaction with 2-iodobenzaldehyde leads to the formation of quinazolines in good yield. 2-Bromobenzaldehyde forms 2-arylquinazolines in low yield due to the competing reaction involving two molecules of amidine leading to a dihydrotriazine.