Tian-Shung Wu, M. Liou, C. Kuoh
Jun 1, 1997
Citations
0
Influential Citations
50
Citations
Quality indicators
Journal
Journal of Natural Products
Abstract
Two related 1H-2,3,3a,8b-tetrahydrocyclopenta[b]benzofurans, aglafolin (1a) and rocaglamide (2), isolated from the stems of Aglaia elliptifolia, showed significant cytotoxicity in six cancer cell lines. Aglafolin (1a) was also found to completely block platelet aggregation caused by arachidonic acid and platelet-activating factor at 100 μM and 2 ng/mL, respectively.