M. Mosaddik, M. Haque
Dec 1, 2003
Citations
3
Influential Citations
83
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Journal
Phytotherapy Research
Abstract
The cytotoxicity and antimicrobial activity of goniothalamin isolated from Bryonopsis laciniosa was investigated. Goniothalamin showed potent cytotoxicity with LC50 values (5.03 µg/mL) comparable with the reference standard agent, gallic acid. It also showed weak antibacterial and significant antifungal activity against a wide range of gram positive and gram negative bacteria and fungi. The antibacterial (minimum inhibitory concentration) effect against Bacillus cereus and Shigella shiga was found to be 64 µg/mL. Copyright © 2003 John Wiley & Sons, Ltd.