Sunaga Kiyoshi, Imamura Toshiko, S. Koide
Sep 1, 1971
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Journal
Journal of Steroid Biochemistry
Abstract
Abstract The reaction of 11β,17α-dihydroxy-1,4-pregnadiene-3,20-dion-21-al (21-dehydroprednisolone) with amino acids was investigated. The rate of reaction as measured by the amount of keto acids formed was most rapid with sodium glutamate. Evidence is presented suggesting that the free γ-carboxylic group of glutamic acid influences the rate of deamination.