S. Vittori, D. Salvatori, R. Volpini
May 1, 2003
Citations
0
Influential Citations
3
Citations
Quality indicators
Journal
Nucleosides, Nucleotides & Nucleic Acids
Abstract
Abstract N6-Cycloalkyl-2′,3′-dideoxyadenosine derivatives and (2-chloro)-N6-cycloheptyl-3-deazaadenosine have been synthesized and tested, along with other (deaza)purine (deoxy)nucleosides from our chemical library, as inhibitors of virus replication against Bovine Herpes Virus 1 (BHV-1) and sheep Maedi/Visna Virus (MVV). Most compounds demonstrated good antireplicative activity against MVV, showing also low cell toxicity.