G. B. Henegouwen, H. J. V. D. Zijde, J. Griend
Mar 1, 1987
Citations
0
Influential Citations
8
Citations
Journal
International Journal of Pharmaceutics
Abstract
Abstract The photodecomposition of diphenhydramine is described: 11 products have been described and a reaction scheme is given. Rearrangement and fission of the side-chain are important routes as well as demethylation of the dimethylamino group. The formation of instable intermediates may be important with respect to photoallergy. reported as a side-effect of diphenhydramine.