Shih-Chang Hsu, Trong-Ming Don, W. Chiu
2002
Citations
3
Influential Citations
208
Citations
Quality indicators
Journal
Polymer Degradation and Stability
Abstract
A thermal dissociation initiator, potassium persulfate (KPS), is added to the chitosan solution at 70 � C; immediately, the solution viscosity and the molecular weight of chitosan decrease in a very short time. Size exclusion chromatography, nuclear magnetic resonance and electron spin resonance were used to study the degradation mechanism. A free radical degradation mechanism of chitosan by KPS is then proposed. When KPS is thermally dissociated into anionic radicals, they are attracted to the cationic amino group in the chitosan ring. Subsequently, the anionic radical attacks the C-4 carbon and transfers the radical to the C-4 carbon by subtracting the hydrogen from it. The presence of free radical at C-4 carbon eventually results in the breakage of the glycosidic C– O–C bond in the chitosan main chain. According to this mechanism, the concentrations of KPS, total free radicals and the degraded chitosan chain at different degradation times are all calculated by solving the rate equations. Finally, the calculated average molecular weights of the degraded chitosan chains at different reaction times agree with the experimental values. # 2001 Elsevier Science Ltd. All rights reserved.