A. Schmidt, A. Lindner, A. Shilabin
Feb 25, 2008
Citations
0
Influential Citations
12
Citations
Journal
Tetrahedron
Abstract
( S )-11-Thioxo-2,3,11,11a-tetrahydro-1 H -benzo[ e ]pyrrolo[1,2- a ][1,4]diazepine-5(10 H )-one was subsequently reacted with amino acid esters and base to give new 6:7:5:5, 6:7:5:6, and 6:5:7:7 ring systems. The 6:7:5:5 ring system, ( S )-11,12,13,13a-tetrahydro-2 H -benzo[ e ]imidazo[2,1- c ]pyrrolo[1,2- a ][1,4]diazepine-3,9-dione, exhibits a considerable CH-acidity at position 2, which was exploited in Knoevenagel reactions, a Wittig reaction, enol ester formations, and methylations.