M. F. Ismail, H. Madkour, M. Salem
Jun 30, 2021
Citations
1
Influential Citations
11
Citations
Journal
Synthetic Communications
Abstract
Abstract 5-(3-Chlorophenyl)-1,3,4-thiadiazol-2-amine 2 was synthesized and employed to synthesize new 1,3,4-thiadiazole and 1,3,4-thiadiazolo[3,2-a]pyrimidine derivatives via reactions with variant electrophilic reagents under solvent-free conditions. The chemical structures of these novel compounds were elucidated scrupulously by aiding elemental data and spectroscopic techniques. The synthesized compounds were evaluated for the insecticidal activity against cotton leaf worm (Spodoptera littoralis). It was realized that the insecticidal activity of 1,3,4-thiadiazolo[3,2-a]pyrimidine derivatives emerged remarkable results comparable with 1,3,4-thiadiazole derivatives against cotton leafworm (Spodoptera littoralis). Graphical abstract