S. Raval, P. Raval, D. Bandyopadhyay
Jul 15, 2008
Citations
0
Influential Citations
6
Citations
Journal
Bioorganic & medicinal chemistry letters
Abstract
Design and synthesis of a novel 3-hydroxy-cyclobut-3-ene-1,2-dione derivatives are reported and their in vitro thyroid hormone receptor selectivity has been evaluated in the thyroid luciferase receptor assay. The 3-[3,5-dichloro-4-(4-hydroxy-3-isopropylphenoxy)-phenylamino]-4-hydroxy-cyclobut-3-ene-1,2-dione 21 has shown selectivity towards thyroid hormone receptor beta.