J. Cook, F. Zusi, Matthew D. Hill
Nov 15, 2017
Citations
1
Influential Citations
3
Citations
Journal
Bioorganic & medicinal chemistry letters
Abstract
We describe an efficient and convergent synthesis of a series of (1'S,2R,4'S)-3H-4'-azaspiro[benzo[4,5]imidazo[2,1-b]oxazole-2,2'-bicyclo[2.2.2]octanes] displaying potency for the α7 nicotinic acetylcholine receptor (nAChR) and good selectivity vs. the related 5-HT3A receptor.