A. B. Durkee, J. Sirois
1964
Citations
0
Influential Citations
28
Citations
Journal
Journal of chromatography
Abstract
Abstract 1. p-Dimethylaminocinnamaldehyde (DMCA) is a more sensitive reagent, in most instances, than the Ehrlich reagent but is less selective in its color reaction and would be rather a poor chromatographic spray when both indoles and aromatic amines are present. 2. DMCA should be used if skatole or indole is assumed to be present on the chromatogram and in conjunction with the Ehrlich reagent if indole-3-acetonitrile and indole-3-acrylic acid are thought to be present. 3. The decreased reactivity of substituted indoles with carbonly or nitrile groups attached directly to the 3-carbon atom suggest that the condensation takes place at the 2-position. 4. The differences in color of indole and benzyloxyindole from the 3-substituted derivatives, indole-3-acetic acid and tryptophan, etc., suggest that their condensation products are of different structure.