Haeri So, Hanna Cho, Hangyul Lee
Jun 1, 2020
Citations
0
Influential Citations
15
Citations
Journal
Microchemical Journal
Abstract
Abstract A novel thiourea-based chemosensor THB (N-benzhydryl-2-(thiophene-2-carbonyl)hydrazine-1-carbothioamide) was designed and investigated. THB had the capability to detect zinc ion and hypochlorite in a near-perfect aqueous media via different fluorescent emission channels. Limits of detection (LOD) were determined to be 0.67 µM for zinc ion and 0.28 µM for hypochlorite. Importantly, THB could successfully monitor both zinc ion and hypochlorite in zebrafish. Response mechanisms of THB to zinc ion and hypochlorite were demonstrated by 1H NMR titrations, theoretical calculations, fluorescent and UV–vis spectral variations, and ESI-mass.