S. Toppet, P. Claes, J. Hoogmartens
1974
Citations
0
Influential Citations
6
Citations
Journal
Magnetic Resonance in Chemistry
Abstract
A study of the 1H and 13C NMR spectra of the N-formyl-2,2,5-trimethyl-4-carboxythiazolidines and the N-formyl-4-carboxy-5-methylthiazolidines derived from the two diastereoisomeric 2-amino-3-mercapto-DL-butyric acids, permits unambiguous assignment of the erythro and threo configuration of these amino acids. The spectra of the N-formylthiazolidines, recorded in DMSO-d6 solution, reveal the presence of two conformational isomers with a low rate of interconversion. The geometry around the carbon–nitrogen bond and correlated conformations of the 5-membered ring in both forms are discussed.