K. A. Connors, K. Albert
May 1, 1973
Citations
0
Influential Citations
46
Citations
Journal
Journal of pharmaceutical sciences
Abstract
Abstract: 4-Dimethylamlnopyridine is an effective catalyst of analytical acylations by acetic anhydride, having a specific catalytic activity about 10 4 times greater than that of pyridine. The conventional titrimetric determination of hydroxy groups is carried out with 4-dimethylaminopyridine as the catalyst and pyridine as the solvent. Typical reaction times for primary and secondary alcohols are 5–10 min. at 54-70°.