Chao He, Qingguo He, C. Deng
Feb 1, 2011
Citations
0
Influential Citations
18
Citations
Journal
Synthetic Metals
Abstract
Abstract Three different poly{9,9-bis[6′(–NHBoc, –NH 3 + and –NH 2 )hexyl]fluorene}s (PF-NHBoc, PF-NH 3 + and PF-NH 2 ) have been synthesized and characterized. Both UV–Vis and fluorescence spectroscopic results supported the interaction between the polyfluorenes and Methamphetamine Hydrochloride (MAPA) was derived from the different terminals of hexyl side chains. Among the three polyfluorenes, PF-NH 2 exhibited the best sensory response to Methamphetamine Hydrochloride (MAPA) in THF arising from its –NH 2 terminals. The fluorescence of PF-NH 2 was immediately quenched once the MAPA was added, and the detection limit of MAPA was determined to be ∼25 ng/mL. Fluorescence quenching experiments of PF-NH 2 by NH 4 Cl and other metal ions confirmed that electrostatic interaction should make contributions to the quenching behavior, in addition, upward non-linear curvature and much higher quenching constant ( K sv ) in the Stern–Volmer plots for MAPA suggested some other interactions such as hydrophobic or/and hydrogen-bonding interactions dominated the analyte-induced aggregation, and such hydrophobic interaction was responsible for the sensitive selectivity. The fluorescent quenching experiments upon adding other drugs such as Pethidine Hydrochloride (PTD) and Ephedrine Hydrochloride (EPD) confirmed such selectivity, especially under the high concentration of the Stern–Volmer plots. The high sensitivity, selectivity, and its simple and fast character, made it a new and effective way for drug detection.