T. Sadanaga, K. Hikida, K. Tameto
Oct 25, 1982
Citations
0
Influential Citations
39
Citations
Journal
Chemical & pharmaceutical bulletin
Abstract
A simple high-performance liquid chromatographic method for the determination of nifedipine, dimethyl 1, 4-dihydro-2, 6-dimethyl-4-(2-nitrophenyl)-3, 5-pyridinedicarboxylate, in plasma is described. The method permits the accurate determination of the drug in plasma at concentrations as low as 2 ng/ml and is suitable for drug monitoring and for investigation of the bioavailabilities of drug preparations.