L. Xi
2015
Citations
0
Influential Citations
1
Citations
Journal
Northwest Pharmaceutical Journal
Abstract
Objective To establish an HPLC method for the determination of the contents of pentoxyverine citrate in Compound Pentoxyverine Citrate Granules.Methods A C18(250mm×4.6mm,5μm)column was used with 1 mL·L-1 triethylamine(pH3.0)-methanol(45︰55)as the mobile phase at a flow rate of 1.0 mL·min-1.The detection wavelength was set at 215nm.The column temperature was 35 ℃.Results The linear range was 0.04-2.0mg·mL-1(r=0.999 9)and the limit of quantification was 4μg·mL.The average recovery was 100.2%(RSD=0.78%).Conclusion The method is simple,accurate and can be used for the quality control.