R. Lambrecht, P. Clarys, R. Clijsen
Aug 1, 2006
Citations
0
Influential Citations
9
Citations
Quality indicators
Journal
Skin Research and Technology
Abstract
Background/aims: In this study, we investigated the bioavailability of iontophoretically delivered diclofenac with the methylnicotinate (MN) test. The inhibition of an erythema provoked by MN is proportional to the bioavailability of diclofenac in the skin. It was our aim to use this procedure in the determination of the contribution of, respectively, passive diffusion, occlusion and electrically assisted delivery during an iontophoretic procedure as used in physiotherapy.