Weijian Chen, Yu-San Ren
Apr 1, 2014
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0
Influential Citations
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Journal
International Journal of Chemical Engineering and Applications
Abstract
New approaches have been developed here: 4-methyl-benzoic acid first reacted with thionyl chloride, then with caprolactam, and last with N-bromosuccinimide to produce the 4-bromomethyl benzoyl caprolactam. Further, N, N, N-triethyl-4-[(hexahydro-2-oxo-1H-azepin-1-yl) carbonyl]-, Bromine was prepared through the reaction with triethylamine and 4-bromomethyl benzoyl caprolactam. The total yield was 61%. 4-methyl-benzoic acid reacted N-bromosuccinimide, then with chlorohydric acid, and last with caprolactam to produce 4 chloromethyl benzoyl caprolactam. N, N, N-triethyl-4-[( hexahydro -2-oxo-1H-azepin-1-yl) carbonyl]-,Chloride was further synthesized via the reaction with triethylamine and 4 chloromethyl benzoyl. The total yield was 41%.