P. Griffin, L. Allan, P. Beckett
Mar 1, 2001
Citations
0
Influential Citations
13
Citations
Journal
Clinical & Experimental Allergy
Abstract
Acid anhydrides are a group of highly reactive chemicals used widely in the formulation of paints and plastics. Exposure to acid anhydrides causes several occupational lung diseases such as pneumonititis and asthma. Whilst anhydrides, specifically trimellitic anhydride (TMA), have been shown to bind to lung tissue in an animal model, further investigation has been hampered by the lack of a reagent which would enable the identification of primary target proteins for the binding of TMA.