A. Zuev, N. P. Sadchikova, I. I. Tyulyaev
Nov 1, 2003
Citations
0
Influential Citations
3
Citations
Journal
Pharmaceutical Chemistry Journal
Abstract
The development of new effective cardiovascular drugs is a currently important task of pharmacy. Carvedilol, or 1-(carbazol-4-yloyl)-3-[[2-O-methoxyphenoxy)ethyl]amino]2-propanol or 1-(9-H-carbazol-4-yloxy)-3-[[2-O-methoxyphenoxy)ethyl]amino]-2-propanol, is a new drug combining the properties of a nonselective -adrenoblocker and a selective -adrenoreceptor antagonist. This drug possesses antioxidant properties, produces vasodilative and hypotensive effect, and suppresses tachycardia. This study was aimed at the composition and technology of production of carvedilol tablets.