Yang Zhang, M. Sigman
Oct 26, 2006
Citations
0
Influential Citations
36
Citations
Journal
Organic letters
Abstract
A general hydroalkoxylation of vinylphenols has been successfully developed wherein primary, secondary, and tertiary alcohols can be used as nucleophiles. The key conceptual breakthrough is the use of sec-phenethyl alcohol at relatively low concentrations as the sacrificial alcohol to undergo oxidation and provide the proposed Pd-H intermediate. [reaction: see text].