B. Lu, Guisheng Li, S. Rodriguez
Jan 11, 2013
Citations
0
Influential Citations
4
Citations
Journal
Synlett
Abstract
The development of synthetic routes to 4-[6-(morpholinomethyl)pyridin-3-yl]naphthalen-1-amine, the key intermediate of p38 MAP kinase inhibitor BIRB 1017, via (1) trialkylmagnesium ate complex mediated metalation and borylation followed by Suzuki coupling reactions and (2) pyridine-ring formation from a vinamidinium salt, is described.