F. Gallou, Manuela Seeger-Weibel, P. Chassagne
Mar 4, 2013
Citations
0
Influential Citations
15
Citations
Journal
Organic Process Research & Development
Abstract
A practical and robust process for the synthesis of an Isatoribine pro-drug was demonstrated. The process relies on a streamlined glycosylation carried out in xylene and an effective regioselective enzymatic hydrolysis that can be run in a semicontinuous way. Analysis of the process mass intensity established the high impact from an environmental standpoint of our process improvement.