K. Sudheesh, S. Harsoor
Jul 1, 2011
Citations
2
Influential Citations
103
Citations
Quality indicators
Journal
Indian Journal of Anaesthesia
Abstract
Dexmedetomidine has become of the frequently used drugs in anaesthetic armamentarium, along with routine anaesthetic drugs, due to its haemodynamic, sedative, anxiolytic, analgesic, neuroprotective and anaesthetic sparing effects. Other claimed advantages include minimal respiratory depression with cardioprotection, neuroprotection and renoprotection, thus making it useful at various situations including offsite procedures.[1] α-1 to α-2 ratio of 1:1600 makes it a highly selective α-2 agonist compared to clonidine, thus reducing the unwanted side effects involving α-1 receptors.