B. Lee, M. Clothier
May 20, 1997
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0
Influential Citations
2
Citations
Journal
Bioorganic & Medicinal Chemistry Letters
Abstract
Abstract The C26 dimethyl dioxepinoindole ring found in marcfortine A is unique among natural products. In order to ascertain the importance of the dimethyl moiety to anthelmintic activity, we prepared a variety of C26-dialkyl and spiroalkyl analogs. They include cyclobutyl, cyclohexyl, diethyl, and ethyl-methyl derivatives. This communication describes the synthesis of these compounds. © 1997 Elsevier Science Ltd.