T. Yan, Ching-Ting Chien, Chia-Chung Tsai
Dec 3, 2004
Citations
0
Influential Citations
22
Citations
Journal
Organic letters
Abstract
[reaction: see text] The successful application of CH2Cl2-Mg-TiCl4-system mediated methylenation of various esters such as tert-butyl ester and 2,5-cyclohexadiene-1-carboxylate highlights the extraordinary reactivity, selectivity, and the nonbasic nature of this new methylene-carbenoid, which serves as a practical reagent applicable to large-scale synthesis.