A. Orellana, S. Pandey, S. Carret
May 29, 2012
Citations
0
Influential Citations
21
Citations
Journal
The Journal of organic chemistry
Abstract
An efficient synthesis of (-)-kainic acid, through a high-pressure-promoted Diels-Alder cycloaddition of a vinylogous malonate derived from 4-hydroxyproline, is described. The bicyclic adduct could be converted into the natural product with complete stereocontrol.