R. Chennoufi, H. Bougherara, N. Gagey-Eilstein
Sep 24, 2015
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Influential Citations
22
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Journal
Chemical communications
Abstract
Triphenylamines are on/off fluorescent DNA minor groove binders, allowing nuclear staining of fixed cells. By contrast, they accumulate in the cytoplasm of living cells and efficiently trigger cell apoptosis upon prolonged visible light irradiation. This process occurs concomitantly with their subcellular re-localization to the nucleus, enabling fluorescence imaging of apoptosis.