T. Tsukamoto, T. Kitazume
1992
Citations
0
Influential Citations
12
Citations
Journal
Journal of The Chemical Society, Chemical Communications
Abstract
New CF2-containing building blocks, ethyl 3-ethoxy-2,2-difluoro-3-hydroxy-propionate and -propioamide, were prepared via formylation of α,α-difluorinated Reformatsky reagents, and reacted with active methylene compounds, nitromethane or phosphonoacetate to afford α,α-difluoro-functionalized esters and amides.