M. Reddy, Avuthu Vidya Sagar Reddy, Y. Jeong
May 1, 2016
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0
Influential Citations
13
Citations
Journal
Research on Chemical Intermediates
Abstract
Abstract In this study, we present a straightforward, efficient and convenient approach for the synthesis of medicinally important 1,4-dihydrobenzo[4,5] imidazo [1,2-a]pyrimidine-3-carboxylates via three-component reactions of aldehydes, 1H-benzo[d]imidazol-2-amine and active methylene compounds in the presence of di-n-butyl ammonium chlorosulfonate ionic liquids (DBA IL) under ultrasound irradiation. This process develops the synthetic potential of ultrasound irradiation with DBA IL combination and presents much compensation, such as outstanding product yields, reusable catalyst, less reaction periods, gainful cost, easy work-up/purification and environmentally benign reaction conditions. Graphical AbstractThe attractive features of this methodology are simple procedure, green reaction, reusability and high efficiency of the catalyst, and easy workability.