Wan‐Chen Pan, Jianquan Liu, Xiang‐Shan Wang
Aug 22, 2018
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0
Influential Citations
3
Citations
Journal
Organic & biomolecular chemistry
Abstract
Dioxane was found to be involved in the reaction of 2-(arylethynyl)benzaldehydes and 3-aminopyrazine-2-carbohydrazide, and underwent a ring-opening reaction catalyzed by AgOTf. This domino type procedure provided an efficient method for the synthesis of 3-aryl-1-(2-(vinyloxy)ethoxy)isoquinolines in good yields via the loss of a molecule of 3-aminopyrazine-2-carboxamide.