G. Noronha, K. Barrett, A. Boccia
Feb 1, 2007
Citations
1
Influential Citations
45
Citations
Journal
Bioorganic & medicinal chemistry letters
Abstract
We describe the identification of [7-(2,6-dichlorophenyl)-5-methylbenzo [1,2,4]triazin-3-yl]-[4-(2-pyrrolidin-1-ylethoxy)phenyl]amine (3), a potent, orally active Src inhibitor with desirable PK properties, demonstrated activity in human tumor cell lines and in animal models of tumor growth.