Matthew W. Martin, J. Newcomb, J. J. Nunes
Apr 15, 2007
Citations
0
Influential Citations
29
Citations
Journal
Bioorganic & medicinal chemistry letters
Abstract
2,3-Diarylfuro[2,3-b]pyridine-4-amines are a novel class of potent and selective inhibitors of Lck. The discovery, synthesis, and structure activity relationships of this series of inhibitors are reported. The most promising compounds were also profiled to deduce their pharmacokinetic properties.